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Toxicology
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ToxicologyTraining Curriculum



TimelineCourse nameCourse#CreditsCourse description
Fall Semester – Year 1Metabolic and Detoxication MechanismsVTPP 6733Fate of foreign compounds; their inhibitory and antagonistic action toward normal metabolic processes of the animal body.
Systemic Physiology IVTPP 6053Aspects of cellular physiology, physiology of excitable membranes, physiology of body fluids, neurophysiology, and the physiology of smooth, cardiac and skeletal muscle; provides a basic understanding of mammalian physiology essential as a framework for advanced graduate studies.
Principles of Human Health Risk Assessment of ChemicalsVTPP 641 3Principles of toxicology and environmental health with the basic concepts and approaches for conducting human health risk assessment of chemicals; use of different types of data and analysis approaches to conduct both qualitative and quantitative assessments of exposure, human health hazard, dose-response, and risk from chemicals in the environment; introduction to how risk assessment informs risk management decisions such as pollution regulations or hazardous waste cleanups.
Experimental Design in BiologyBIOL 683 3Design of scientific research projects in the field of biology; a wide range of biological experiments designed with the appropriate statistical technique for analysis; design biological studies that are statistically tractable and perform basic statistical analyses using the statistical programming language R.
Spring Semester – Year 1Advanced ToxicologyVTPP 670 3Detailed overview of organ-specific effects of toxic substances, organ/tissue-oriented modules that will review basic anatomy and physiology, site-specific metabolism of xenobiotics, mechanisms of toxicity and experimental systems that are used to study toxic effects.
Practice of Evaluating Human Health Risks of ChemicalsVTPP 6452Basic principles of toxicology and environmental health with real-life examples of how diverse types of information are integrated for the purpose of judging what chemical exposures may pose a risk to human health.
Scientific EthicsVMID 686 1Ethical issues of research and methods for resolution of such issues; overview of ethical issues encountered by scientists in the conduct and dissemination of their research, in their pursuit of resources, in their interactions with the press and the broader public and resulting from the extension and technological application of their findings.
PharmacologyVTPP 6253Introduction to pharmacokinetics and pharmacodynamics; survey of major pharmaceutical classes; uses, mechanisms of action and adverse reactions of selected agents. 
Fall Semester – Year 2HistologyVIBS 602 4Molecular phenomena placed in context with tissues, organs and organ systems; cell and tissue structures visualized by light microscopy and electron micrographs for functional relationships; clinical correlations reveal relevance of histology in specific disease states; conceptual thinking exercises facilitate problem-solving skills. 
Journal ClubPHEO 6811Review and discussion of contemporary toxicology literature
Toxicology SeminarVTPP 681 1Review and discussion of current scientific work in physiology and related subjects.
Elective Course3 

Highly Recommended Elective Courses

  • VIBS 690 Theory of Research (Proposal Development)
  • PHEO 605 Chemical Hazard Exposure (Environmental Focus)
  • VTPP 619 Food Toxicology II (Environmental Focus)
  • VIBS 611 Tumor Cell Biology and Carcinogenesis (Mechanistic Focus)

Relevant Elective Courses

  • PHEB 602 Biostatistics I
  • PHEB 603 Biostatistics II
  • VIBS 607 Applied Epidemiology
  • VIBS 660 Reporting Science and Technology
  • VIBS 663 Biomedical Reporting
  • VIBS 664 Risk and Crisis Reporting

Environmental Focus

  • PHEO 630 Environmental/Occupational Diseases
  • PHEO 645 Health and Safety at Hazardous Waste Sites
  • CVEN 601 Environmental Engineering Processes III

Mechanistic Focus

  • VPAT 640 Mechanisms of Disease
  • VTMI 649 Immunology

Recommended Graduate Certificate

Bioinformatics and Computational Biology Certificate (CERT-BICB)

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